BRCA1 silencing is associated with failure of DNA repairing in retinal neurocytes.

BRCA1 silencing is associated with failure of DNA repairing in retinal neurocytes.

Retinal post-mitotic neurocytes display genomic instability after damage induced by physiological or pathological factors. The involvement of BRCA1, an important factor in development and DNA repair in mature retinal neurocytes remains unclear. Thus, we investigated the developmental expression prof...

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Bibliographic Details
Main Authors: Pei Chen, Huan Hu, Zhao Chen, Xiaoxiao Cai, Zhang Zhang, Ying Yang, Na Yu, Jing Zhang, Lei Xia, Jian Ge, Keming Yu, Jing Zhuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4053421?pdf=render

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