Relationship between the type of non-small cell lung cancer and infiltration of lymphatic drainage

• Main Authors: Grbić Kemal, Hadžismailović Ademir, Udovčić-Gagula Dalma, Kantar Marko, Domuzin Marinko
• Format: Article
• Language: English
• Published: Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine 2017-01-01
• Series: Scripta Medica
• Subjects: nsclc; type of tumor; lymph nodes
• Online Access: https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2017/2490-33291702096G.pdf

Introduction: Malignant cells invasion of lymphatic drainage represents the basic precondition of metastasis and the disease progress. The invasion of tumor depends on its pathomorphologic characteristics, out of which one of the most significant role is the type. Aim of the Study: Descriptive analysis of operated patients, estimation of frequency and representativeness of the stated types of NSCLC in the monitored group, analysis of malignant cells of lung cancer in lymphatic drainage on the basis of the type of primary tumor. Patients and Methods: The study included 331 patients, who underwent the surgery during which the malignant infiltration was removed, in addition to the dissection of lymph nodes drainage. Results: Out of the total number of operated patients, 257 of them were male gender, while 74 were female gender, with the average age of 63.52 years (21-80). The relation of gender structure of the patients in relation to gender was statistically significant (p=0.00). The ratio between squamous cell carcinoma to adenocarcinoma was 182:140, while the other types of tumor were insignificant. Statistically, there was no significant difference in the frequency of two most common types of lung cancer (χ2test= 3.02; p=0.09). There was no statistically significant connection between the type of tumor and N1 metastasis (χ2=1.55; p=0.46), as well as in the ratio between the type of tumor and malignant infiltration of lymph nodes, level N2 (χ2=2.33; p=0.32). Conclusion: There is no connection between the type of lung cancer and invasion of levels N1 and N2 of lymph nodes.