The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer
Autophagy, a process of cellular self-degradation and cell survival whereby the cell generates energy and metabolic intermediates under conditions of stress (i.e., nutrient deprivation), is also commonly induced in tumor cells in response to chemotherapy and radiation. While chemotherapy-induced aut...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Biology |
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| Online Access: | https://www.mdpi.com/2079-7737/9/1/12 |