Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan

Caloric restriction (CR), defined as decreased nutrient intake without causing malnutrition, has been documented to increase both health and lifespan across numerous organisms, including humans. Many drugs and other compounds naturally occurring in our diet (nutraceuticals) have been postulated to a...

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Bibliographic Details
Main Authors: Zoe E. Gillespie, Joshua Pickering, Christopher Eskiw
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00142/full