Epistatic role of the MYH9/APOL1 region on familial hematuria genes.

Epistatic role of the MYH9/APOL1 region on familial hematuria genes.

Familial hematuria (FH) is explained by at least four different genes (see below). About 50% of patients develop late proteinuria and chronic kidney disease (CKD). We hypothesized that MYH9/APOL1, two closely linked genes associated with CKD, may be associated with adverse progression in FH. Our stu...

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Bibliographic Details
Main Authors: Konstantinos Voskarides, Panayiota Demosthenous, Louiza Papazachariou, Maria Arsali, Yiannis Athanasiou, Michalis Zavros, Kostas Stylianou, Dimitris Xydakis, Eugenios Daphnis, Daniel P Gale, Patrick H Maxwell, Avraam Elia, Cristian Pattaro, Alkis Pierides, Constantinos Deltas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3597641?pdf=render

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