CXCL12-PLGA/Pluronic Nanoparticle Internalization Abrogates CXCR4-Mediated Cell Migration

CXCL12-PLGA/Pluronic Nanoparticle Internalization Abrogates CXCR4-Mediated Cell Migration

Chemokine-induced chemotaxis mediates physiological and pathological immune cell trafficking, as well as several processes involving cell migration. Among them, the role of CXCL12/CXCR4 signaling in cancer and metastasis is well known, and CXCR4 has been often targeted with small molecule-antagonist...

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Bibliographic Details
Main Authors:	Anissa Pisani, Roberto Donno, Arianna Gennari, Giulia Cibecchini, Federico Catalano, Roberto Marotta, Pier Paolo Pompa, Nicola Tirelli, Giuseppe Bardi
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	Nanomaterials
Subjects:	nanoparticles chemokines chemokine-receptor cell-migration immune cells cancer
Online Access:	https://www.mdpi.com/2079-4991/10/11/2304

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