Impact of Sensitization and Inflammation on the Interaction of Mast Cells With the Intestinal Epithelium in Rats

Impact of Sensitization and Inflammation on the Interaction of Mast Cells With the Intestinal Epithelium in Rats

The density of intestinal mast cells has been reported to increase during inflammatory bowel disease (IBD). As mast cell mediators are known to increase the permeability of epithelial tight junctions, we hypothesized that antigen responses in sensitized animals might be enhanced under inflammatory c...

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Bibliographic Details
Main Authors: Jasmin Becker, Daniela Ott, Martin Diener
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
claudins
colitis
inflammation
intestinal secretion
mast cells
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00329/full

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