Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells

Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells

Connexin 43 (Cx43) forms gap junctions that mediate the direct intercellular diffusion of ions and small molecules between adjacent cells. Cx43 displays both pro- and anti-tumorigenic properties, but the mechanisms underlying these characteristics are not fully understood. Tunneling nanotubes (TNTs)...

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Bibliographic Details
Main Authors: Alexander Tishchenko, Daniel D. Azorín, Laia Vidal-Brime, María José Muñoz, Pol Jiménez Arenas, Christopher Pearce, Henrique Girao, Santiago Ramón y Cajal, Trond Aasen
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
connexin 43
gap junctions
cancer
intercellular communication
breast cancer
cell signaling
Online Access:https://www.mdpi.com/2072-6694/12/10/2798

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