Modeling the Glomerular Filtration Barrier and Intercellular Crosstalk

Modeling the Glomerular Filtration Barrier and Intercellular Crosstalk

The glomerulus is a compact cluster of capillaries responsible for blood filtration and initiating urine production in the renal nephrons. A trilaminar structure in the capillary wall forms the glomerular filtration barrier (GFB), composed of glycocalyx-enriched and fenestrated endothelial cells adh...

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Bibliographic Details
Main Authors: Kerstin Ebefors, Emelie Lassén, Nanditha Anandakrishnan, Evren U. Azeloglu, Ilse S. Daehn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
glomerular filtration barrier
crosstalk
in vitro
podocyte
glomerular endothelial cell
3D model
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.689083/full

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