Bilateral Basal Ganglia Lesions Associated with Lactic Acidosis in an End-Stage Renal Failure Patient

Although bilateral basal ganglia lesions are common in hypoxic encephalopathy and methanol intoxication, they are a rare finding in end-stage chronic renal failure. The pathophysiology of both bilateral and selective involvement of the basal ganglia is unclear, but severe metabolic acidosis is one o...

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Bibliographic Details
Main Authors: Babürhan Güldiken1, Sedat Üstündağ2, Arif Yılmaz1, Hasan Çakır2
Format: Article
Language:English
Published: Galenos Yayinevi 2009-03-01
Series:Türk Nöroloji Dergisi
Subjects:
Online Access:http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-97658
Description
Summary:Although bilateral basal ganglia lesions are common in hypoxic encephalopathy and methanol intoxication, they are a rare finding in end-stage chronic renal failure. The pathophysiology of both bilateral and selective involvement of the basal ganglia is unclear, but severe metabolic acidosis is one of the affected processes. In this report bilateral basal ganglia lesions and accompanying signs, which ensued after the use of metformin in a patient with chronic renal failure, are discussed
ISSN:1301-062X
1309-2545