| Summary: | Amare Getaye,1 Niguss Cherie,1 Getaw Walle Bazie,1 Teshome Gebremeskel Aragie2 1Wollo University, College of Medicine and Health Sciences, School of Public Health, Dessie, Ethiopia; 2Woldia University, College of Health Sciences, Department of Anatomy, Woldia, EthiopiaCorrespondence: Amare GetayeWollo University, College of Medicine and Health Sciences, School of Public Health, Dessie, EthiopiaEmail agetaye@gmail.comBackground: Depression is the most prevalent among people living with HIV/AIDS than people without HIV/AIDS. Depression is associated with an increase in morbidity and mortality in people living with HIV/AIDS and adversely affects the adherence to antiretroviral therapy, quality of life, and health-related parameters.Objective: The aim of this study was to assess the proportion of depression and its associated factors among youth HIV/AIDS patients attending ART clinics in Dessie town Government health facilities, Northeast Ethiopia.Methods: Institutional-based cross-sectional study design was employed on 431 youth HIV/AIDS patients attending ART clinics at Dessie town Public health facilities. Data were collected by face-to-face interview using a structured questionnaire. EPI-Data software version 3.1 was used to enter the data and analysis was done using SPSS version 23. Binary logistic regression was used to identify factors associated with depression. Statistical significance was declared at a p-value of less than 0.05 in the final model.Results: The proportion of depression among youth HIV/AIDS patients was 26.2%. The age range between 20 and 24 years (AOR = 2.019, 95% CI: 1.143– 3.566), poor medication adherence (AOR = 9.007, 95% CI: 3.061– 26.500), stigma (AOR = 4.14, 95% CI: 2.08– 8.26), and low social support (AOR = 1.854, 95% CI: 1.034– 3.324) were associated with depression.Conclusion: The proportion of depression among youth HIV patients in the current study was found to be lower compared to previous studies. Age, HIV-related stigma, social support, lost job, and poor medication adherence were found to be independent predictors of depression. Therefore, scaling up the pediatric psychosocial support program to youth psychosocial support for all ART site health facilities, strengthening health education about the medication adherence and complication of HIV/AIDS are needed.Keywords: depression, Ethiopia, HIV/AIDS, youth
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