RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response

A proper DNA damage response (DDR), which monitors and maintains the genomic integrity, has been considered to be a critical barrier against genetic alterations to prevent tumor initiation and progression. The representative tumor suppressor p53 plays an important role in the regu...

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Bibliographic Details
Main Authors: Toshinori Ozaki, Akira Nakagawara, Hiroki Nagase
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2013/271347