Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis

Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis

Hyperglycemia exposure results in the dysfunction of endothelial cells (ECs) and the development of diabetic complications. Circular RNAs (circRNAs) have been demonstrated to play critical roles in EC dysfunction. The current study aimed to explore the role and mechanism of circRNA CLIP–associating...

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Bibliographic Details
Main Authors: Qin Zhang, Jing Long, Nannan Li, Xuelian Ma, Lisheng Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
high glucose
circ_CLASP2
miR-140-5p
Fbxw7
ECs dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.594793/full

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