SLC39A8 gene encoding a metal ion transporter: discovery and bench to bedside

SLC39A8 gene encoding a metal ion transporter: discovery and bench to bedside

Abstract SLC39A8 is an evolutionarily highly conserved gene that encodes the ZIP8 metal cation transporter in all vertebrates. SLC39A8 is ubiquitously expressed, including pluripotent embryonic stem cells; SLC39A8 expression occurs in every cell type examined. Uptake of ZIP8-mediated Mn2+, Zn2+, Fe2...

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Bibliographic Details
Main Authors: Daniel W. Nebert, Zijuan Liu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Human Genomics
Subjects:
ZIP8 transporter
SLC39A8 gene
Manganese uptake
Zinc uptake
Iron uptake
Selenium uptake
Online Access:http://link.springer.com/article/10.1186/s40246-019-0233-3

Internet

http://link.springer.com/article/10.1186/s40246-019-0233-3

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