Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case

Integrating photoacoustic (PA) and ultrasound (US) into a handheld probe to perform PA/US dual-modal imaging has been widely studied over the past few years. However, optical fluence decreases quickly in deeper tissue due to light scattering and absorption, which would significantly affect the quant...

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Main Authors:	Lingyi Zhao, Meng Yang, Yuxin Jiang, Changhui Li
Format:	Article
Language:	English
Published:	World Scientific Publishing 2017-07-01
Series:	Journal of Innovative Optical Health Sciences
Subjects:	PA imaging ultrasound optical fluence
Online Access:	http://www.worldscientific.com/doi/pdf/10.1142/S1793545817400028

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spelling	doaj-6ff1be23ab3a49209e4680ef1f8cbbb72020-11-24T21:25:50ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052017-07-011041740002-11740002-810.1142/S179354581740002810.1142/S1793545817400028Optical fluence compensation for handheld photoacoustic probe: An in vivo human study caseLingyi Zhao0Meng Yang1Yuxin Jiang2Changhui Li3Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, ChinaDepartment of Ultrasonography, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Ultrasonography, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, ChinaIntegrating photoacoustic (PA) and ultrasound (US) into a handheld probe to perform PA/US dual-modal imaging has been widely studied over the past few years. However, optical fluence decreases quickly in deeper tissue due to light scattering and absorption, which would significantly affect the quantitative PA imaging. In this paper, we performed a fluence compensation for a PA imaging study of human breast. The comparison of PA/US image with and without optical fluence compensation demonstrated that the fluence compensation could effectively improve imaging quality for handheld probe.http://www.worldscientific.com/doi/pdf/10.1142/S1793545817400028PA imagingultrasoundoptical fluence
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Lingyi Zhao Meng Yang Yuxin Jiang Changhui Li
spellingShingle	Lingyi Zhao Meng Yang Yuxin Jiang Changhui Li Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case Journal of Innovative Optical Health Sciences PA imaging ultrasound optical fluence
author_facet	Lingyi Zhao Meng Yang Yuxin Jiang Changhui Li
author_sort	Lingyi Zhao
title	Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case
title_short	Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case
title_full	Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case
title_fullStr	Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case
title_full_unstemmed	Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case
title_sort	optical fluence compensation for handheld photoacoustic probe: an in vivo human study case
publisher	World Scientific Publishing
series	Journal of Innovative Optical Health Sciences
issn	1793-5458 1793-7205
publishDate	2017-07-01
description	Integrating photoacoustic (PA) and ultrasound (US) into a handheld probe to perform PA/US dual-modal imaging has been widely studied over the past few years. However, optical fluence decreases quickly in deeper tissue due to light scattering and absorption, which would significantly affect the quantitative PA imaging. In this paper, we performed a fluence compensation for a PA imaging study of human breast. The comparison of PA/US image with and without optical fluence compensation demonstrated that the fluence compensation could effectively improve imaging quality for handheld probe.
topic	PA imaging ultrasound optical fluence
url	http://www.worldscientific.com/doi/pdf/10.1142/S1793545817400028
work_keys_str_mv	AT lingyizhao opticalfluencecompensationforhandheldphotoacousticprobeaninvivohumanstudycase AT mengyang opticalfluencecompensationforhandheldphotoacousticprobeaninvivohumanstudycase AT yuxinjiang opticalfluencecompensationforhandheldphotoacousticprobeaninvivohumanstudycase AT changhuili opticalfluencecompensationforhandheldphotoacousticprobeaninvivohumanstudycase
_version_	1725982438821199872

Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case

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