Optical fluence compensation for handheld photoacoustic probe: An in vivo human study case

Integrating photoacoustic (PA) and ultrasound (US) into a handheld probe to perform PA/US dual-modal imaging has been widely studied over the past few years. However, optical fluence decreases quickly in deeper tissue due to light scattering and absorption, which would significantly affect the quant...

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Bibliographic Details
Main Authors: Lingyi Zhao, Meng Yang, Yuxin Jiang, Changhui Li
Format: Article
Language:English
Published: World Scientific Publishing 2017-07-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545817400028
Description
Summary:Integrating photoacoustic (PA) and ultrasound (US) into a handheld probe to perform PA/US dual-modal imaging has been widely studied over the past few years. However, optical fluence decreases quickly in deeper tissue due to light scattering and absorption, which would significantly affect the quantitative PA imaging. In this paper, we performed a fluence compensation for a PA imaging study of human breast. The comparison of PA/US image with and without optical fluence compensation demonstrated that the fluence compensation could effectively improve imaging quality for handheld probe.
ISSN:1793-5458
1793-7205