Asymmetric RNA Distribution among Cells and Their Secreted Exosomes: Biomedical Meaning and Considerations on Diagnostic Applications

Asymmetric RNA Distribution among Cells and Their Secreted Exosomes: Biomedical Meaning and Considerations on Diagnostic Applications

Over the past few years, exosomes and their RNA cargo have been extensively studied because of the fascinating biological roles they play in cell-to-cell communication, including the signal exchange among cancer, stromal, and immune cells, leading to modifications of tumor microenvironment. RNAs, es...

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Bibliographic Details
Main Authors: Marco Ragusa, Cristina Barbagallo, Matilde Cirnigliaro, Rosalia Battaglia, Duilia Brex, Angela Caponnetto, Davide Barbagallo, Cinzia Di Pietro, Michele Purrello
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
exosomes
RNAs
RNA sorting
biomarkers
cancer
asymmetric molecular distribution
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00066/full

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