Synthesis and Biological Evaluation of Metronidazole Derivatives as Anti-Giardia Agents

Synthesis and Biological Evaluation of Metronidazole Derivatives as Anti-Giardia Agents

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Nitroimidazole derivatives such as Metronidazole (MTZ) have been used as anti- protozoa and anti-anaerobic bacteria. In this study several derivatives of MTZ were synthesized and evaluated against Giardia lamblia cyst. MTZ were reacted with several alkyl halide to obtain o-alkyl MTZ derivatives, the...

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Bibliographic Details
Main Authors: Bahador Shahriari, Zahra Rezaei, Soghra Khabnadideh, Hossein Sadeghpour, Gholam Reza Hatam, Qasem Asgari, Amin Kiani, Fardad Firoozi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-06-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Nitromidazole
Metronidazole derivatives
Antigiarida.
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/34/40

Internet

http://tips.sums.ac.ir/index.php/TiPS/article/view/34/40

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