Intestinal Long-Chain Fatty Acids Act as a Direct Signal To Modulate Expression of the Salmonella Pathogenicity Island 1 Type III Secretion System

Intestinal Long-Chain Fatty Acids Act as a Direct Signal To Modulate Expression of the Salmonella Pathogenicity Island 1 Type III Secretion System

Salmonella enterica serovar Typhimurium uses the Salmonella pathogenicity island 1 (SPI1) type III secretion system (T3SS) to induce inflammatory diarrhea and bacterial uptake into intestinal epithelial cells. The expression of hilA, encoding the transcriptional activator of the T3SS structural gene...

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Bibliographic Details
Main Authors: Yekaterina A. Golubeva, Jeremy R. Ellermeier, Jessica E. Cott Chubiz, James M. Slauch
Format: Article
Language:English
Published: American Society for Microbiology 2016-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/1/e02170-15

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