MET/PKCß expression correlate with metastasis and inhibition is synergistic in lung cancer

MET/PKCß expression correlate with metastasis and inhibition is synergistic in lung cancer

<b>Background: </b> Treatment of non-small cell lung cancer (NSCLC) remains a difficult task in oncology. Targeted inhibition of oncogenic proteins is promising. In this study, we evaluate the expression of MET and PKC&#223; and in vitro effects of their inhibition using SU11274 and...

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Bibliographic Details
Main Authors: Faoro Leonardo, Cervantes Gustavo, Ferguson Benjamin, Seiwert Tanguy, Yala Soheil, Vigneswaran Wicki, Westerhoff Maria, Tretiakova Maria, Ferguson Mark, Moura Glaci, Husain Aliya, Vokes Everett, Salgia Ravi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Journal of Carcinogenesis
Subjects:
c-MET
developmental therapeutics
lung cancer
protein kinase C
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2009;volume=8;issue=1;spage=15;epage=15;aulast=Faoro

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http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2009;volume=8;issue=1;spage=15;epage=15;aulast=Faoro

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