Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway

Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway

Abstract Background Cisplatin is one of the first-line drugs for urothelial bladder cancer (UBC) treatment. However, its considerable side effects and the emergence of drug resistance are becoming major limitations for its application. This study aimed to investigate whether matrine and cisplatin co...

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Bibliographic Details
Main Authors: Xiao-Zhong Liao, Lan-Ting Tao, Jia-Hui Liu, Yue-Yu Gu, Jun Xie, Yuling Chen, Mei-Gui Lin, Tao-Li Liu, Dong-Mei Wang, Hai-Yan Guo, Sui-Lin Mo
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Cancer Cell International
Subjects:
Matrine
Cisplatin
Combination
Synergistic effect
EJ
T24
Online Access:http://link.springer.com/article/10.1186/s12935-017-0495-6

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