Influence of polymethacrylates and compritol on release profile of a highly water soluble drug metformin hydrochloride

Aims: The present investigation studied effect of polymethacrylates Eudragit RSPO, Eudragit RLPO and compritol 888 ATO on release profile of highly water soluble drug metformin hydrochloride (MET). Materials and Methods: The solid dispersions were prepared using drug:polymer ratios 1:1 and 1:5 by co...

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Bibliographic Details
Main Authors: Sunita Dahiya, Raginee Onker
Format: Article
Language:English
Published: Facultad de Farmacia, Universidad de Granada 2015-01-01
Series:Ars Pharmaceutica
Subjects:
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942015000100004&lng=en&tlng=en