A Data Fusion Approach to Enhance Association Study in Epilepsy.
Among the scientific challenges posed by complex diseases with a strong genetic component, two stand out. One is unveiling the role of rare and common genetic variants; the other is the design of classification models to improve clinical diagnosis and predictive models for prognosis and personalized...
Main Authors: | Simone Marini, Ivan Limongelli, Ettore Rizzo, Alberto Malovini, Edoardo Errichiello, Annalisa Vetro, Tan Da, Orsetta Zuffardi, Riccardo Bellazzi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5161322?pdf=render |
Similar Items
-
RB1CC1 duplication and aberrant overexpression in a patient with schizophrenia: further phenotype delineation and proposal of a pathogenetic mechanism
by: Edoardo Errichiello, et al.
Published: (2021-01-01) -
Phenotypic Expansion in Nasu-Hakola Disease: Immunological Findings in Three Patients and Proposal of a Unifying Pathogenic Hypothesis
by: Edoardo Errichiello, et al.
Published: (2019-07-01) -
A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients
by: Monica Cattaneo, et al.
Published: (2017-12-01) -
Phenotype forecasting with SNPs data through gene-based Bayesian networks
by: Puca Annibale A, et al.
Published: (2009-02-01) -
Big Data as a Driver for Clinical Decision Support Systems: A Learning Health Systems Perspective
by: Arianna Dagliati, et al.
Published: (2018-05-01)