Chronic circadian advance shifts abolish melatonin secretion for days in rats
Melatonin deficiency has been proposed to underlie higher risks for cardiovascular and several other diseases in humans experiencing prolonged shiftwork. However, melatonin secretion has not been monitored longitudinally during consecutive shifts of the light:dark (LD) cycles in the same individuals...
Main Authors: | Gang Xu, Jon Dean, Tiecheng Liu, Fangyun Tian, Jimo Borjigin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-06-01
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Series: | Neurobiology of Sleep and Circadian Rhythms |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2451994417300354 |
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