Chronic circadian advance shifts abolish melatonin secretion for days in rats

Melatonin deficiency has been proposed to underlie higher risks for cardiovascular and several other diseases in humans experiencing prolonged shiftwork. However, melatonin secretion has not been monitored longitudinally during consecutive shifts of the light:dark (LD) cycles in the same individuals...

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Bibliographic Details
Main Authors: Gang Xu, Jon Dean, Tiecheng Liu, Fangyun Tian, Jimo Borjigin
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Neurobiology of Sleep and Circadian Rhythms
Online Access:http://www.sciencedirect.com/science/article/pii/S2451994417300354