A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female

Background. Disseminated tuberculosis (TB) has been increasingly recognized in adults in the recent times due to increased prevalence of immune suppression. Here we describe a case of 47-year-old female who presented with disproportionate ascites where the diagnosis of disseminated TB was delayed. C...

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Main Authors: Sahathevan Vithoosan, Ponnudurai Shanjeeban, Joseph Philip Anpalahan, Paramarajan Piranavan, Harindra Karunatilake, Ananda Jayanaga
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2019/5076857
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spelling doaj-6fb2246804ca4ad59087a6fa325db4ed2020-11-25T00:02:41ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65282090-65362019-01-01201910.1155/2019/50768575076857A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged FemaleSahathevan Vithoosan0Ponnudurai Shanjeeban1Joseph Philip Anpalahan2Paramarajan Piranavan3Harindra Karunatilake4Ananda Jayanaga5National Hospital, Colombo, Sri LankaNational Hospital, Colombo, Sri LankaNational Hospital, Colombo, Sri LankaInternal Medicine, Saint Vincent Hospital, Worcester, MA 01608, USANational Hospital, Colombo, Sri LankaNational Hospital, Colombo, Sri LankaBackground. Disseminated tuberculosis (TB) has been increasingly recognized in adults in the recent times due to increased prevalence of immune suppression. Here we describe a case of 47-year-old female who presented with disproportionate ascites where the diagnosis of disseminated TB was delayed. Case Report. A 47-year-old previously healthy female presented with generalised body swelling with disproportionate ascites and loss of appetite and weight for four-month duration. She denied any contact or past history of TB and reported no respiratory symptoms. Physical examination revealed significant ascites. There was no lymphadenopathy or hepatosplenomegaly. Respiratory system examination was normal. Her Erythrocyte Sedimentation Rate (ESR) was above 100. Tuberculin skin test was positive with 17mm. Contrast Enhanced Computed Tomography (CECT) abdomen revealed chronic liver disease with ascites. Diagnostic laparoscopy was in favour of miliary TB and the peritoneal biopsy revealed granulomatous inflammation with caseous necrosis, suggestive of TB. The patient was started on antituberculosis treatment and subsequently improved. Conclusion. TB peritonitis due to disseminated TB should be considered in the differential diagnosis of disproportionate ascites. Even though the diagnosis is difficult, diagnostic laparoscopy and biopsy is very helpful. It is important to have an early diagnosis since delay in treatment can be detrimental in most cases.http://dx.doi.org/10.1155/2019/5076857
collection DOAJ
language English
format Article
sources DOAJ
author Sahathevan Vithoosan
Ponnudurai Shanjeeban
Joseph Philip Anpalahan
Paramarajan Piranavan
Harindra Karunatilake
Ananda Jayanaga
spellingShingle Sahathevan Vithoosan
Ponnudurai Shanjeeban
Joseph Philip Anpalahan
Paramarajan Piranavan
Harindra Karunatilake
Ananda Jayanaga
A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
Case Reports in Gastrointestinal Medicine
author_facet Sahathevan Vithoosan
Ponnudurai Shanjeeban
Joseph Philip Anpalahan
Paramarajan Piranavan
Harindra Karunatilake
Ananda Jayanaga
author_sort Sahathevan Vithoosan
title A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
title_short A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
title_full A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
title_fullStr A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
title_full_unstemmed A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
title_sort rare cause of ascites-disseminated tb with peritonitis in a middle-aged female
publisher Hindawi Limited
series Case Reports in Gastrointestinal Medicine
issn 2090-6528
2090-6536
publishDate 2019-01-01
description Background. Disseminated tuberculosis (TB) has been increasingly recognized in adults in the recent times due to increased prevalence of immune suppression. Here we describe a case of 47-year-old female who presented with disproportionate ascites where the diagnosis of disseminated TB was delayed. Case Report. A 47-year-old previously healthy female presented with generalised body swelling with disproportionate ascites and loss of appetite and weight for four-month duration. She denied any contact or past history of TB and reported no respiratory symptoms. Physical examination revealed significant ascites. There was no lymphadenopathy or hepatosplenomegaly. Respiratory system examination was normal. Her Erythrocyte Sedimentation Rate (ESR) was above 100. Tuberculin skin test was positive with 17mm. Contrast Enhanced Computed Tomography (CECT) abdomen revealed chronic liver disease with ascites. Diagnostic laparoscopy was in favour of miliary TB and the peritoneal biopsy revealed granulomatous inflammation with caseous necrosis, suggestive of TB. The patient was started on antituberculosis treatment and subsequently improved. Conclusion. TB peritonitis due to disseminated TB should be considered in the differential diagnosis of disproportionate ascites. Even though the diagnosis is difficult, diagnostic laparoscopy and biopsy is very helpful. It is important to have an early diagnosis since delay in treatment can be detrimental in most cases.
url http://dx.doi.org/10.1155/2019/5076857
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