Cannabis-based treatment induces polarity-reversing plasticity assessed by theta burst stimulation in humans

Cannabis-based treatment induces polarity-reversing plasticity assessed by theta burst stimulation in humans

Background: In animal models, the cannabinoid system has been convincingly implicated in the regulation of long-lasting synaptic plasticity. Both long-term potentiation (LTP) and depression (LTD) phenomena can be induced in the human motor cortex by transcranial magnetic theta burst stimulation (TBS...

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Main Authors: Giacomo Koch, MD, PhD, Francesco Mori, MD, Claudia Codecà, MD, Hajime Kusayanagi, MD, Fabrizia Monteleone, MD, Fabio Buttari, MD, Stefania Fiore, MD, Giorgio Bernardi, MD, Diego Centonze, MD
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Brain Stimulation
Subjects:
cannabinoid receptors
LTD
LTP
metaplasticity
Sativex
TBS
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X09000138

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