Alteration of pancreatic cancer cell functions by tumor-stromal cell interaction

Pancreatic cancer shows a characteristic tissue structure called desmoplasia, which consists of dense fibrotic stroma surrounding cancer cells. Interactions between pancreatic cancer cells and stromal cells promote invasive growth of cancer cells and establish a specific microenvironment such as hyp...

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Bibliographic Details
Main Authors: Shin eHamada, Atsushi eMasamune, Tooru eShimosegawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00318/full