Role of NADPH oxidase pathway in renal protection induced by procyanidin B2: In L-NAME induced rat hypertension model

Role of NADPH oxidase pathway in renal protection induced by procyanidin B2: In L-NAME induced rat hypertension model

The present study examined the effects of procyanidin B2 (PB2) on L-NAME (nitric oxide synthase inhibitor)-induced hypertensive nephropathy. After 4 weeks of treatment with daily PB2 supplementation, lower blood pressure levels were observed in rats. The potential mechanisms were combined with ameli...

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Bibliographic Details
Main Authors: Hong Ding, Xiaofei Li, Jian Li, Zhike Li, Yunhui Niu, Wanying Ren, Jianyang Tan, Shanye Yin
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Functional Foods
Subjects:
Hypertension
Renal damage
Apoptosis
NADPH oxidase
Procyanidin B2
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618301440

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