Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II

Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II

Cholinomimetic activity of p, N- (3, 4-methylene dioxy phenyl) benzoic acid was revealed while studying its hypotensive activity in cats. Further evaluation of this activity showed that this com-pound had both muscarinic and nicotinic components. The cholino-mimetic activity was not similar to antic...

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Main Authors: Dahanukar Sharadini, Sheth U
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 1978-01-01
Series:Journal of Postgraduate Medicine
Online Access:http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=3;spage=177;epage=181;aulast=Dahanukar
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spelling doaj-6f98157412e14784844ba704e651968f2020-11-25T00:42:09ZengWolters Kluwer Medknow PublicationsJournal of Postgraduate Medicine0022-38590972-28231978-01-01243177181Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-IIDahanukar SharadiniSheth UCholinomimetic activity of p, N- (3, 4-methylene dioxy phenyl) benzoic acid was revealed while studying its hypotensive activity in cats. Further evaluation of this activity showed that this com-pound had both muscarinic and nicotinic components. The cholino-mimetic activity was not similar to anticholinesterase like activity. Species variation was present; in rats it failed to show any activity and no activity was exhibited in vitro suggesting some metabolic transformation.http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=3;spage=177;epage=181;aulast=Dahanukar
collection DOAJ
language English
format Article
sources DOAJ
author Dahanukar Sharadini
Sheth U
spellingShingle Dahanukar Sharadini
Sheth U
Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II
Journal of Postgraduate Medicine
author_facet Dahanukar Sharadini
Sheth U
author_sort Dahanukar Sharadini
title Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II
title_short Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II
title_full Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II
title_fullStr Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II
title_full_unstemmed Pharmacological Studies of p, N-(3, 4-Methylenedioxy Phenyl) Benzoic Acid (RRL-1364) - part-II
title_sort pharmacological studies of p, n-(3, 4-methylenedioxy phenyl) benzoic acid (rrl-1364) - part-ii
publisher Wolters Kluwer Medknow Publications
series Journal of Postgraduate Medicine
issn 0022-3859
0972-2823
publishDate 1978-01-01
description Cholinomimetic activity of p, N- (3, 4-methylene dioxy phenyl) benzoic acid was revealed while studying its hypotensive activity in cats. Further evaluation of this activity showed that this com-pound had both muscarinic and nicotinic components. The cholino-mimetic activity was not similar to anticholinesterase like activity. Species variation was present; in rats it failed to show any activity and no activity was exhibited in vitro suggesting some metabolic transformation.
url http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=3;spage=177;epage=181;aulast=Dahanukar
work_keys_str_mv AT dahanukarsharadini pharmacologicalstudiesofpn34methylenedioxyphenylbenzoicacidrrl1364partii
AT shethu pharmacologicalstudiesofpn34methylenedioxyphenylbenzoicacidrrl1364partii
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