Down-Regulation of NFkB, Bax,TGF-β, Smad-2mRNA expression in the Livers of Carbon Tetrachloride Treated Rats using Different Natural Antioxidants

The objective of this study is to examine whether silymarin alone or in combination with chlorogenic acid and/ or melatonin plays a modulatory role against apoptotic damage in rats liver induced by of CCl4. The present work revealed that CCl4 induced elevation of in Bax, Smad, TGF-β and NFkBhepatic...

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Bibliographic Details
Main Authors: Nouf Mohamed Al-Rasheed, Laila Mohamed Fadda, Nawal Mohamed Al-Rasheed, Hanaa Mahmoud Ali, Hazar Ibrahim Yacoub
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar)
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100408&lng=en&tlng=en