A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome

A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome

Abstract Background Advancements in Next Generation Sequencing (NGS) technologies regarding throughput, read length and accuracy had a major impact on microbiome research by significantly improving 16S rRNA amplicon sequencing. As rapid improvements in sequencing platforms and new data analysis pipe...

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Bibliographic Details
Main Authors: Imane Allali, Jason W. Arnold, Jeffrey Roach, Maria Belen Cadenas, Natasha Butz, Hosni M. Hassan, Matthew Koci, Anne Ballou, Mary Mendoza, Rizwana Ali, M. Andrea Azcarate-Peril
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Microbiology
Subjects:
16S rRNA amplicon sequencing - microbiome analysis - microbiome - microbiome composition - next generation sequencing platforms
Bioinformatics pipeline
NGS bias
Online Access:http://link.springer.com/article/10.1186/s12866-017-1101-8

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