LukS‐PV induces apoptosis in acute myeloid leukemia cells mediated by C5a receptor

LukS‐PV induces apoptosis in acute myeloid leukemia cells mediated by C5a receptor

Abstract LukS‐PV is one of the two components of Panton‐Valentine leucocidin (PVL). Our previous study showed that LukS‐PV can induce apoptosis in human acute myeloid leukemia (AML) THP‐1 and HL‐60 cells. C5aR (C5a receptor) is the receptor for PVL, but whether C5aR plays a key role in LukS‐PV induc...

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Bibliographic Details
Main Authors: Peng Zhang, Wen‐Wei Yu, Jing Peng, Liang‐Fei Xu, Chang‐Cheng Zhao, Wen‐Jiao Chang, Xiao‐Ling Ma
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Cancer Medicine
Subjects:
AML
C5a receptor
LukS‐PV
molecular marker
therapeutic target
Online Access:https://doi.org/10.1002/cam4.2137

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