PEGylated Polyethylenimine Derivative-Mediated Local Delivery of the shSmad3 Inhibits Intimal Thickening after Vascular Injury

PEGylated Polyethylenimine Derivative-Mediated Local Delivery of the shSmad3 Inhibits Intimal Thickening after Vascular Injury

Intimal hyperplasia is a complex process which contributes to several clinical problems such as atherosclerosis and postangioplasty restenosis. Inhibition of Smad3 expression inhibits intimal thickening. Our previous study has modified biscarbamate cross-linked polyethylenimine derivative (PEI-Et) t...

Full description

Bibliographic Details
Main Authors:	Yu Wang, Danyang Zhao, Xiao Wei, Lin Ma, Jing Sheng, Ping Lu
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2019/8483765

Similar Items

MicroRNA delivery mediated by PEGylated polyethylenimine for prostate cancer therapy
by: CY Chen, et al.
Published: (2018-12-01)

Effects of PEGylated and Quaternized Polyethylenimines on Gene Transfection Efficiency
by: Yu-Chi Huang, et al.
Published: (2013)

Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury
by: Tian S, et al.
Published: (2015-09-01)

Experimental aortic intimal thickening /
by: Webster, William Sprigg
Published: (1973)

Transcription Factors Targeted by miRNAs Regulating Smooth Muscle Cell Growth and Intimal Thickening after Vascular Injury
by: Levon M. Khachigian
Published: (2019-10-01)

Losartan reduces collagen content and intimal thickening of iliac arteries after balloon injury in rabbits
by: Jianhua Zhu, et al.
Published: (2000-09-01)

Gene delivery mediated by cyanophycin- polyethylenimine conjugates
by: Pei-Ying Lin, et al.
Published: (2014)

Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo
by: Morishita Y, et al.
Published: (2015-05-01)

Effects of vitamin C treatment on collar-induced intimal thickening
by: Arun MZ, et al.
Published: (2015-12-01)

Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
by: Sante Di Gioia, et al.
Published: (2008-09-01)

The synthesis and characterisation of modified polyethylenimine polymers for gene delivery
by: Brownlie, Anthony
Published: (2002)

The Effect of Polyethylenimine on the Cationic Liposome Gene Delivery System
by: Shao-Chun, Wu, et al.
Published: (2007)

Study of polyethylenimine-based antisense oligonucleotide delivery system
by: Yun-Jen Chan, et al.
Published: (2008)

Crosslinked linear polyethylenimine enhances delivery of DNA to the cytoplasm
by: Bonner, Daniel K., et al.
Published: (2016)

Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease
by: Denise Burtenshaw, et al.
Published: (2019-08-01)

Efficient miRNA Inhibitor Delivery with Graphene Oxide-Polyethylenimine to Inhibit Oral Squamous Cell Carcinoma
by: Ou L, et al.
Published: (2020-03-01)

Sugars grafted on polyethylenimine affect the buffering capacity of polyethylenimine
by: Jia-jian Jhang, et al.
Published: (2007)

SIMVASTATIN INCORPORATED PERIVASCULAR POLYMERIC CONTROLLED DRUG DELIVERY SYSTEM FOR THE INHIBITION OF VASCULAR WALL INTIMAL HYPERPLASIA
by: Krishnan, Aadithya
Published: (2007)

Polyethylenimine and liposome-based non-viral vectors for gene delivery /
by: Gosselin, Michael A.
Published: (2002)

A Polyethylenimine-Linoleic Acid Conjugate for Antisense Oligonucleotide Delivery
by: Jing Xie, et al.
Published: (2013-01-01)

Grafting chitosan with polyethylenimine in an ionic liquid for efficient gene delivery.
by: Huiying Chen, et al.
Published: (2015-01-01)

Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery
by: Huang XZ, et al.
Published: (2014-10-01)

Synthesis of novel polyurethane grafted polyethylenimine as DNA delivery vectors
by: Pan,Kuang-Hung, et al.
Published: (2016)

New amphiphilic polyethylenimines (PEIs) for oral delivery of poorly soluble drugs and DNA vaccines
by: Cheng, Woei Ping
Published: (2005)

ShRNA-mediated knock-down of CD200 using the self-assembled nanoparticle-forming derivative of polyethylenimine
by: Bahman Khalvati, et al.
Published: (2019-07-01)

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system
by: Paula M. Castillo, et al.
Published: (2014-08-01)

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine
by: Yue Yin, et al.
Published: (2018-08-01)

PEGylation of Polyethylenimine Lowers Acute Toxicity while Retaining Anti-Biofilm and β‑Lactam Potentiation Properties against Antibiotic-Resistant Pathogens
by: Anh K. Lam, et al.
Published: (2020-09-01)

Preparation and Evaluation of PEGylated and Folate-PEGylated Liposomes Containing Paclitaxel for Lymphatic Delivery
by: Hea-Young Cho, et al.
Published: (2015-01-01)

Perivascular Drug Delivery Systems for the Inhibition of Intimal Hyperplasia
by: Kanjickal, Deenu George
Published: (2005)

The relationship between wall shear stress distributions and intimal thickening in the human abdominal aorta
by: Butany Jagdish, et al.
Published: (2003-11-01)

Mechanisms and prevention of intimal thickening of the autogenous vein grafts : possible involvement of nitric oxide
by: Komori, Kimihiro
Published: (2003)

Highly Osmotic Oxidized Sucrose-Crosslinked Polyethylenimine for Gene Delivery Systems
by: Jaehong Park, et al.
Published: (2021-01-01)

Synthesis and Evaluation of Tetramethylguanidinium-Polyethylenimine Polymers as Efficient Gene Delivery Vectors
by: Manohar Mahato, et al.
Published: (2014-01-01)

Amino Acid-Modified Polyethylenimines with Enhanced Gene Delivery Efficiency and Biocompatibility
by: Qin-Fang Zhang, et al.
Published: (2015-11-01)

Engineering polyethylenimine- Based gene delivery vectors with improved transfection efficiency
by: Aravindan, Latha
Published: (2010)

pH-Responsive Cross-Linked Low Molecular Weight Polyethylenimine as an Efficient Gene Vector for Delivery of Plasmid DNA Encoding Anti-VEGF-shRNA for Tumor Treatment
by: Xiaoming Li, et al.
Published: (2018-09-01)

Amino Acid-Linked Low Molecular Weight Polyethylenimine for Improved Gene Delivery and Biocompatibility
by: Xiao-Ru Wu, et al.
Published: (2020-02-01)

Folate-Mediated Targeted Delivery of siPLK1 by Leucine-Bearing Polyethylenimine
by: Hou L, et al.
Published: (2020-03-01)

Cholic Acid-Conjugated Methylcellulose-Polyethylenimine Nano-Aggregates for Drug Delivery Systems
by: Taewan Kim, et al.
Published: (2019-03-01)