Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents

Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents

Necroptotic cell death is characterized by an activation of RIPK3 and MLKL that leads to plasma membrane permeabilization and the release of immunostimulatory cellular contents. High levels of chondrocyte death occur following intra-articular trauma, which frequently leads to post-traumatic osteoart...

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Bibliographic Details
Main Authors: Josef Stolberg-Stolberg, Meike Sambale, Uwe Hansen, Alexandra Schäfer Michael Raschke, Jessica Bertrand, Thomas Pap, Joanna Sherwood
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
necroptosis
post-traumatic arthritis
cell death
inflammation
articular cartilage
Online Access:https://www.mdpi.com/1422-0067/21/12/4204

Internet

https://www.mdpi.com/1422-0067/21/12/4204

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