Small molecule control of virulence gene expression in Francisella tularensis.
In Francisella tularensis, the SspA protein family members MglA and SspA form a complex that associates with RNA polymerase (RNAP) to positively control the expression of virulence genes critical for the intramacrophage growth and survival of the organism. Although the association of the MglA-SspA c...
Main Authors: | James C Charity, Leeann T Blalock, Michelle M Costante-Hamm, Dennis L Kasper, Simon L Dove |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-10-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2763202?pdf=render |
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