28-day repeated oral dose toxicity study of an aqueous extract of Gryllus bimaculatus in sprague-dawley rat

This study was performed to demonstrate a No Observed Adverse Effect Level (NOAEL) for an aqueous extract of Gryllus bimaculatus. According to other studies, using dried material or extract with ethanol or methanol determined a NOAEL dose of 1000 mg/kg or 5000 mg/kg in rats. Therefore, the Gryllus b...

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Bibliographic Details
Main Authors: Su Hyun Yu, Su-Yeol Yu, Bo-Su Lee, Hyun-Jin Kim, Mi-Ran Kim, Young-Chul Lee
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750019300678