Evaluation of genetic risk score models in the presence of interaction and linkage disequilibrium
In the area of genetic epidemiology, genetic risk predictive modeling is becoming an important area of translational success. As an increasing number of genetic variants are successfully discovered, the use of multiple genetic variants in constructing a genetic risk score (GRS) for modeling has bee...
Main Authors: | Ronglin eChe, Alison eMotsinger-Reif |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-07-01
|
Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00138/full |
Similar Items
-
Extent of third-order linkage disequilibrium in a composite line of Iberian pigs
by: Luis Gomez-Raya, et al.
Published: (2018-08-01) -
Linkage disequilibrium measures for fine-scale mapping of disease loci are revisited
by: Carlos eZapata
Published: (2013-11-01) -
A survey of data mining methods for linkage disequilibrium mapping
by: Onkamo Päivi, et al.
Published: (2006-03-01) -
Distribution of genome-wide linkage disequilibrium based on microsatellite loci in the Samoan population
by: Tsai Hui-Ju, et al.
Published: (2004-08-01) -
Linkage disequilibrium mapping for grain Fe and Zn enhancing QTLs useful for nutrient dense rice breeding
by: S. K. Pradhan, et al.
Published: (2020-02-01)