Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism
Mitochondria are highly dynamic organelles that play a central role in multiple cellular processes, including energy metabolism, calcium homeostasis and apoptosis. Miro proteins (Miros) are “atypical” Ras superfamily GTPases that display unique domain architecture and subcellular localisation regula...
Main Authors: | Daniel T. Peters, Laura Kay, Jeyanthy Eswaran, Jeremy H. Lakey, Meera Soundararajan |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-12-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/19/12/3839 |
Similar Items
-
MIRO GTPases in Mitochondrial Transport, Homeostasis and Pathology
by: Bor Luen Tang
Published: (2015-12-01) -
Cell signaling by Rho and Miro GTPases : Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics
by: Fransson, Åsa
Published: (2008) -
DISC1 Regulates Mitochondrial Trafficking in a Miro1-GTP-Dependent Manner
by: Rosalind Norkett, et al.
Published: (2020-06-01) -
The mitochondrial Ras-related GTPase Miro: views from inside and outside the metazoan kingdom
by: Shohei eYamaoka, et al.
Published: (2014-07-01) -
Activated Rho GTPases in Cancer—The Beginning of a New Paradigm
by: Pontus Aspenström
Published: (2018-12-01)