Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism

Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism

Mitochondria are highly dynamic organelles that play a central role in multiple cellular processes, including energy metabolism, calcium homeostasis and apoptosis. Miro proteins (Miros) are “atypical” Ras superfamily GTPases that display unique domain architecture and subcellular localisation regula...

Full description

Bibliographic Details
Main Authors: Daniel T. Peters, Laura Kay, Jeyanthy Eswaran, Jeremy H. Lakey, Meera Soundararajan
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
Miro
atypical GTPases
monomeric GTPase
GTPase mechanism
mitochondrial movement
NTPase
Online Access:https://www.mdpi.com/1422-0067/19/12/3839

Internet

https://www.mdpi.com/1422-0067/19/12/3839

Similar Items