Spreading depolarization evoked by endothelin-1 is inhibited by octanol but not by carbenoxolone
Spreading depolarization (SD) has been implicated in the pathogenesis of delayed cerebral ischemia (DCI) after subarachnoid hemorrhage. Endothelin-1 (ET-1) is a powerful trigger of SD and may be involved in DCI. The SD-causing mechanism is assumed to result from ET-1-induced microarterial spasm and...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2021-03-01
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Series: | Brain Hemorrhages |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589238X20300425 |