Novel knowledge about the influence of hepatitis C virus structural proteins ratio in vaccine preparations to induce a protective immune response in a challenge model with a surrogate virus

Novel knowledge about the influence of hepatitis C virus structural proteins ratio in vaccine preparations to induce a protective immune response in a challenge model with a surrogate virus

The incomplete definition of immunologic parameters that correlates with the protection against HCV infection has limited the development of a vaccine against this pathogen. Several studies advocate for the induction of strong cellular immune response against viral antigens, as well as neutralizing...

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Bibliographic Details
Main Authors: Alexis Musacchio, Gillian Martínez, Liz Alvarez-Lajonchere, Ivis Guerra, Nelson Acosta, Yalena Amador, Angel Pérez, Yordanka Soria, Pedro Puentes, Santiago Dueñas
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
protective immune response
hepatitis c
structural antigens
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522011000300010&lng=en&tlng=en

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