Targeted deep sequencing from multiple sources demonstrates increased NOTCH1 alterations in lung cancer patient plasma

Targeted deep sequencing from multiple sources demonstrates increased NOTCH1 alterations in lung cancer patient plasma

Abstract Introduction Targeted therapies are based on specific gene alterations. Various specimen types have been used to determine gene alterations, however, no systemic comparisons have yet been made. Herein, we assessed alterations in selected cancer‐associated genes across varying sample sites i...

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Bibliographic Details
Main Authors: Yuwei Liao, Zhaokui Ma, Yu Zhang, Dan Li, Dekang Lv, Zhisheng Chen, Peiying Li, Aisha AI‐Dherasi, Feng Zheng, Jichao Tian, Kun Zou, Yue Wang, Dongxia Wang, Miguel Cordova, Huan Zhou, Xiuhua Li, Dan Liu, Ruofei Yu, Qingzheng Zhang, Xiaolong Zhang, Jian Zhang, Xuehong Zhang, Xia Zhang, Yulong Li, Yanyan Shao, Luyao Song, Ruimei Liu, Yichen Wang, Sufiyan Sufiyan, Quentin Liu, Gareth I. Owen, Zhiguang Li, Jun Chen
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Cancer Medicine
Subjects:
lung cancer
next‐generation sequencing
NOTCH1
plasma
pleural effusion
Online Access:https://doi.org/10.1002/cam4.2458

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