SARS-CoV-2: from its discovery to genome structure, transcription, and replication

Abstract SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant genetic shift from different isolates. Af...

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Bibliographic Details
Main Authors: Ayslan Castro Brant, Wei Tian, Vladimir Majerciak, Wei Yang, Zhi-Ming Zheng
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cell & Bioscience
Online Access:https://doi.org/10.1186/s13578-021-00643-z