Human Peripheral Blood Eosinophils Express High Levels of the Purinergic Receptor P2X4

Human Peripheral Blood Eosinophils Express High Levels of the Purinergic Receptor P2X4

Extracellular nucleotides are important mediators of cell activation and trigger multiple responses via membrane receptors known as purinergic receptors (P2). P2X receptors are ligand-gated ion channels, activated by extracellular ATP. P2X4 is one of the most sensitive purinergic receptors, that is...

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Bibliographic Details
Main Authors: Viiu Paalme, Airi Rump, Kati Mädo, Marina Teras, Birgit Truumees, Helen Aitai, Kristel Ratas, Mickael Bourge, Chi-Shiun Chiang, Aram Ghalali, Thierry Tordjmann, Jüri Teras, Pierre Boudinot, Jean M. Kanellopoulos, Sirje Rüütel Boudinot
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
P2X4 purinergic receptor
monoclonal antibody
eosinophils
PBL marker
gender difference
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02074/full

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