Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations
Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with oligosaccharides and provide molecular insights into the function, and into associated diseases.
Main Authors: | Liting Zhai, Lingling Feng, Lin Xia, Huiyong Yin, Song Xiang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11229 |
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