Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations

Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with oligosaccharides and provide molecular insights into the function, and into associated diseases.

Bibliographic Details
Main Authors: Liting Zhai, Lingling Feng, Lin Xia, Huiyong Yin, Song Xiang
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11229
Description
Summary:Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with oligosaccharides and provide molecular insights into the function, and into associated diseases.
ISSN:2041-1723