Three-dimensional ultrastructure of giant mitochondria in human non-alcoholic fatty liver disease

Abstract Giant mitochondria are peculiarly shaped, extremely large mitochondria in hepatic parenchymal cells, the internal structure of which is characterised by atypically arranged cristae, enlarged matrix granules and crystalline inclusions. The presence of giant mitochondria in human tissue biops...

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Bibliographic Details
Main Authors: Gerald J. Shami, Delfine Cheng, Pauline Verhaegh, Ger Koek, Eddie Wisse, Filip Braet
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82884-z