Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication

Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication

Abstract Background The influenza matrix protein (M1) layer under the viral membrane plays multiple roles in virus assembly and infection. N-domain and C-domain are connected by a loop region, which consists of conserved RQMV motif. Methods The function of the highly conserve RQMV motif in the influ...

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Bibliographic Details
Main Authors: Petra Švančarová, Tatiana Betáková
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Virology Journal
Subjects:
Influenza a virus
M1 protein
NP protein
CLUH
Reverse genetic
Online Access:http://link.springer.com/article/10.1186/s12985-018-1056-x

Internet

http://link.springer.com/article/10.1186/s12985-018-1056-x

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