Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders

• Main Authors: Keun-A Chang, Jun-Ho Lee, Yoo-Hun Suh
• Format: Article
• Language: English
• Published: Elsevier 2014-04-01
• Series: Journal of Pharmacological Sciences
• Online Access: http://www.sciencedirect.com/science/article/pii/S1347861319300878

Abstract.: Stem cell therapy has been noted as a novel strategy to various diseases including neurological disorders such as Alzheimer’s disease, Parkinson’s disease, stroke, amyotrophic lateral sclerosis, and Huntington’s disease that have no effective treatment available to date. The adipose-derived stem cells (ASCs), mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency with the ability to differentiate into various types of cells and immuno-modulatory property. These biological features make ASCs a promising source for regenerative cell therapy in neurological disorders. Here we discuss the recent progress of regenerative therapies in various neurological disorders utilizing ASCs. Keywords:: neurological disorder, adipose-derived stem cell (ASC), Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD)